Archive

Annika Hunziker (group SST)

Luca Murer (group UG)

Enterovirus particles expel capsid pentamers to enable genome release

EPS8 Facilitates Uncoating of Influenza A Virus

Idoia Busnadiego (group BGH)

Fanny Georgi (group UG)

Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer

Hepatitis Delta Virus Alters the Autophagy Process To Promote Its Genome Replication

Matthias Glögl (group AT)

Jacob Börold (group BGH)

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

NO Progress Meeting

NO Progress Meeting

Easter Monday, NO Journal Club

04.02.2019

Davide Eletto (Group BGH)

Luca Murer (group UG)

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency

18.02.2019

Matteo Bianchi (group AT)

Daniele Sequeira (group UG)

Pseudovirus rVSVDG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice

Late activation of the Raf/MEK/ERK pathway is required for translocation of the respiratory syncytial virus F protein to the plasma membrane and efficient viral replication

04.03.2019

Nora Schmidt (group BGH)

Merle Schanz (group AT)

Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed -1 Ribosomal Frameshifting

Evolution of the Envelope Glycoprotein of HIV-1 Clade B towards Higher Infectious2 Properties over the Course of the Epidemic

18.03.2019

Annika Hunziker (group SST)

Sonja Harms (group BGH)

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex

01.04.2019

Friedrich Nikolas (group AT)

Umut Karakus (group SST)

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

Influenza binds phosphorylated glycans from human lung

15.04.2019

Idoia Busnadiego (group BGH)

Harini Subbaraman (group AT)

Methyltransferase SETD2-Mediated Methylation ofSTAT1 Is Critical for Interferon Antiviral Activity

The repertoire of maternal anti-viral antibodiesin human newborns

29.04.2019

Eva Spieler (group SST/BGH)

Anthony Petkidis (Group UG)

ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADPribosylating the ubiquitin E3 ligase β-TrCP

Chloroviruses lure hosts through long-distance chemical signaling

13.05.2019

Matthias Glögl (group AT)

Fanny Georgi (group UG)

Complement C4 Prevents Viral Infection through Capsid Inactivation

A multicellular way of life for a multipartite virus

27.05.2019

Liridona Maliqui (group AT)

Jacob Börold (group BGH)

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling

10.06.2019

24.06.2019

Olszewski Dominik (group UG)

Verena Kufner (group AT)

Adenovirus 5 E1A Interacts with E4orf3 To Regulate Viral Chromatin Organization

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis

08.07.2019

No Journal Club

22.07.2019

Sira Günther (group SSt)

Romain Volle (group UG)

Influenza Virus Exploits an Interferon-Independent lncRNA to Preserve Viral RNA Synthesis through Stabilizing Viral RNA Polymerase PB1

Polyamine Depletion Inhibits Bunyavirus Infection via Generation of Noninfectious Interfering Virions

Anthony Petkidis (Group UG)

Sonja Harms (group BGH)

Nanoscale Polarization of the Vaccinia Virus Entry Fusion Complex Drives Efficient Fusion

Nuclear-resident RIG-I senses viral replication inducing antiviral immunity

Fanny Georgi (group UG)

Liridona Maliqui (group AT)

The mobility of packaged phage genome controls ejection dynamics

Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer

Jacob Börold (group BGH)

Olszewski Dominik (group UG)

A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity

Verena Kufner (group AT)

Marie-Theres Pohl (group SSt)

Field-deployable viral diagnostics using CRISPR-Cas13

Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus

Janine Vetter (group SSt)

Differentiated human airway organoids to assess infectivity of emerging influenza virus

Martinez Lopez Itzel (group UG)

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

NO Journal Club

Sira Günther (group SSt)

Romain Volle (group UG)

The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells

Gómez González Alfonso (group UG)

NP220 mediates silencing of unintegrated retroviral DNA

Caio Foulkes (group AT)

Naoures Khabthani (group SH)

A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

Interferon-induced Transmembrane Protein  restricts replication of  virus that enter cells via the plasma membrane

Davide Eletto (Group BGH)

Michel Crameri (group JP)

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations

TRIM29 promotes DNA virus infections by inhibiting innate immune response

Elizaveta Elshina (Group SSt)

Chris Brunner (group AT)

Influenza A Virus Negative Strand RNA is Translated for CD8+ T Cell Immunosurveillance

Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles

Prasad Vibhu (Group UG)

Matthias Glögl (group AT)

Inflammasome activation triggers caspase-1-mediated cleavage of cGAS to regulate responses to DNA virus infection

An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism

Domingues Patricia (group BGH)

Tania Jetzer (Group SH)

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication

Zika virus has oncolytic activity against glioblastomastem cells

Friedrich Nikolas (group AT)

Eva Spieler (group SST/BGH)

Evolution of a designed protein assembly encapsulating its own RNA genome

Demethylase JMJD6 as a New Regulator of Interferon Signaling:Effects of HCV and Ethanol Metabolism

Annika Hunziker (group SSt)

Michael Bauer (Group UG)

A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

Umut Karakus (group SST)

Idoia Busnadiego (group BGH)

Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation

Cyclin-dependent kinase activity is required for type I interferon production

Claus Kadelka (group AT)

Luca Murer (group UG)

Fitness landscape of the human immunodeficiency virus envelope protein that is targeted by antibodies

Protein composition of the hepatitis A  virus quasi-envelope

Hannah Turkington (group BGH)

Harini Subbaraman (group AT)

PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

SUMO2 and SUMO3 redundantly prevent a noncanonical type I interferon response

Robert Witte (group UG)

Caio Foulkes (Group AT)

Fiona Steiner (Group JP)

Antibody-dependent enhancement of severe dengue disease in humans

A Global Interactome Map of the Dengue Virus NS1 Identifies Virus Restriction and Dependency Host Factors